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Kinetic Model Optimization in Cancer Molecular Imaging

Session Date
ENGR 499-04
5/21 - 7/13/2018


In this undergraduate research immersion-team based course, students will be exposed to modern aspects of molecular imaging in cancer: including an introduction to technological advancements in system development, image reconstruction, and data analysis. There will be an emphasis on quantitative molecular imaging approaches based on tracer kinetic modeling of molecular targeted imaging agents. Based on these principles, in Summer 2015, the student will be asked to explore the effect of biomolecule-imaging agent saturation on estimations of biomolecule concentration. The student will develop mathematical models to describe this and compare to preclinical data collected in mouse models of human cancer. (CRN:33796)